Histological and Immunohistochemical Evaluation of Local Exogenous Application of the Green Tea on Bone Healing (Experimental Study On Rats)

Enas Fadhil


Background: The study was designed to identify the role of local exogenous green tea in bone healing .
Material and method: Thirty male albino rats, were subjected for bone defects in medial sides of both tibia bone (right tibia was considered as experimental site with 1μl of extract green tea, while the left be the control one, (treated with 1μl of normal saline). The rats were scarified at 3,7,10 days post surgery. Bone healing was histologically examined with immunohistochemical for local- ization of bone morphogenic protein 2.
Results: show bone healing treated with extracted green tea illustrated to be faster in apposition of ostoid and bone trabeculae that is detected to fill the most of bone defect in comparism with control group.
Conclusion: Our results indicate that low application of exogenous green tea could be an effective therapeutic for bone injures, these data are promising for a possible future clinical usage especially for enhancement of bone healing. 

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DOI: http://dx.doi.org/10.26477/idj.v38i2.85


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